Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
VIM | P08670 | vimentin | 0.71 | 0.372 | 0.846 | |
PCNA | P12004 | proliferating cell nuclear antigen | Nucleic acid binding | 0.98 | 0.382 | 0.846 |
NFKB1 | P19838 | nuclear factor kappa B subunit 1 | Transcription factor | 1.00 | 0.396 | 0.923 |
CD40 | P25942 | CD40 molecule | 0.85 | 0.396 | 0.846 | |
CYP19A1 | P11511 | cytochrome P450 family 19 subfamily A member 1 | Enzyme | 1.7E-05 | 0.410 | 0.885 |
CYP2D6 | P10635 | cytochrome P450 family 2 subfamily D member 6 | 1.1E-25 | 0.437 | 0.885 | |
CHD7 | Q9P2D1 | chromodomain helicase DNA binding protein 7 | 1.00 | 0.441 | 0.846 | |
HSPA5 | P11021 | heat shock protein family A (Hsp70) member 5 | 0.77 | 0.434 | 0.885 | |
CXCR2 | P25025 | C-X-C motif chemokine receptor 2 | G-protein coupled receptor | 1.4E-02 | 0.445 | 0.923 |
RYR1 | P21817 | ryanodine receptor 1 | Ion channel | 1.6E-29 | 0.489 | 0.808 |
ZEB1 | P37275 | zinc finger E-box binding homeobox 1 | Transcription factor | 0.97 | 0.442 | 0.808 |
TPM3 | P06753 | tropomyosin 3 | Cellular structure | 6.7E-03 | 0.490 | 0.808 |
CUX1 | P39880 Q13948 | cut like homeobox 1 | Transcription factor | 1.00 | 0.465 | 0.846 |