Disease: Charcot-Marie-Tooth Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MBS2 Moebius syndrome 2 0.931 0.115
CMTX3 Charcot-Marie-Tooth neuropathy, X-linked 3 (dominant) 0.821 0.154
DNAJB2 P25686 DnaJ heat shock protein family (Hsp40) member B2 5.4E-05 0.743 0.192
PMP2 P02689 peripheral myelin protein 2 8.5E-03 0.769 0.231
JPH1 Q9HDC5 junctophilin 1 0.77 0.705 0.269
SLC25A46 Q96AG3 solute carrier family 25 member 46 Transporter 1.3E-05 0.695 0.308
SPTLC2 O15270 serine palmitoyltransferase long chain base subunit 2 Enzyme 0.78 0.736 0.346
SH3TC2 Q8TF17 SH3 domain and tetratricopeptide repeats 2 8.3E-16 0.666 0.385
INF2 Q27J81 inverted formin, FH2 and WH2 domain containing 0.97 0.644 0.423
DGAT2 Q96PD7 diacylglycerol O-acyltransferase 2 Enzyme 8.4E-12 0.686 0.423
AARS1 P49588 alanyl-tRNA synthetase 1 Nucleic acid binding 1.8E-08 0.647 0.462
GJB3 O75712 gap junction protein beta 3 Cell-cell junction 2.2E-03 0.621 0.462
LITAF Q99732 lipopolysaccharide induced TNF factor Transcription factor 3.1E-02 0.650 0.462
MORC2 Q9Y6X9 MORC family CW-type zinc finger 2 1.00 0.626 0.462
YARS2 Q9Y2Z4 tyrosyl-tRNA synthetase 2 Enzyme 3.0E-11 0.663 0.462
FGD4 Q96M96 FYVE, RhoGEF and PH domain containing 4 Enzyme modulator 9.8E-03 0.678 0.462
GARS1 P41250 glycyl-tRNA synthetase 1 Enzyme 0.31 0.623 0.500
PDK3 Q15120 pyruvate dehydrogenase kinase 3 Kinase 0.45 0.678 0.500
SBF1 O95248 SET binding factor 1 Enzyme 1.00 0.700 0.500
GAN Q9H2C0 gigaxonin 2.5E-02 0.674 0.500
YARS1 P54577 tyrosyl-tRNA synthetase 1 Enzyme 1.0E-03 0.705 0.500
RNMT O43148 RNA guanine-7 methyltransferase 5.7E-05 0.647 0.500
SLC12A6 Q9UHW9 solute carrier family 12 member 6 Transporter 1.1E-02 0.603 0.500
LRSAM1 Q6UWE0 leucine rich repeat and sterile alpha motif containing 1 3.1E-13 0.638 0.500
MTMR2 Q13614 myotubularin related protein 2 Enzyme 3.0E-07 0.659 0.538