Disease: Nystagmus, CTCAE 5.0
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
RPE65 Q16518 retinoid isomerohydrolase RPE65 Enzyme 6.5E-14 0.417 0.808
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808
TTR P02766 transthyretin Transporter 0.52 0.423 0.885
SMARCB1 Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 1.00 0.434 0.846
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
PAX6 P26367 paired box 6 1.00 0.450 0.769
TNFSF11 O14788 TNF superfamily member 11 Signaling 4.9E-03 0.453 0.846
CYP1B1 Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 2.2E-05 0.457 0.769
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
BEST1 O76090 bestrophin 1 Ion channel 1.8E-12 0.465 0.885
DHDDS Q86SQ9 dehydrodolichyl diphosphate synthase subunit Enzyme 0.25 0.468 0.885
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808
SDHD O14521 succinate dehydrogenase complex subunit D Transporter 0.34 0.472 0.885
TYR P14679 tyrosinase Enzyme 5.0E-32 0.473 0.808
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
SCN1A P35498 sodium voltage-gated channel alpha subunit 1 Ion channel 1.00 0.477 0.808
FOXC1 Q12948 forkhead box C1 Transcription factor 0.95 0.483 0.846
SLC52A2 Q9HAB3 solute carrier family 52 member 2 Transporter 2.5E-03 0.483 0.808