Disease: Chronic pain
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808
CACNA1H O95180 calcium voltage-gated channel subunit alpha1 H Ion channel 4.8E-10 0.628 0.423
CALCA P01258 P06881 calcitonin related polypeptide alpha Signaling 1.6E-02 0.416 0.923
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
CNR2 P34972 cannabinoid receptor 2 G-protein coupled receptor 6.5E-06 0.509 0.846
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
KNG1 P01042 kininogen 1 Enzyme modulator 3.2E-10 0.481 0.885
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
NTF3 P20783 neurotrophin 3 Signaling 0.93 0.519 0.808
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
P2RX2 Q9UBL9 purinergic receptor P2X 2 Ion channel 9.7E-13 0.585 0.769
P2RX3 P56373 purinergic receptor P2X 3 Ion channel 1.0E-06 0.565 0.769
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577
PRKCE Q02156 protein kinase C epsilon Kinase 1.00 0.597 0.692
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
SLC12A5 Q9H2X9 solute carrier family 12 member 5 Transporter 1.00 0.570 0.654
TRPA1 O75762 transient receptor potential cation channel subfamily A member 1 Ion channel 7.2E-35 0.546 0.846
TRPV1 Q8NER1 transient receptor potential cation channel subfamily V member 1 Ion channel 1.0E-16 0.446 0.885
VIP P01282 vasoactive intestinal peptide Signaling 4.2E-04 0.437 0.846