Disease: Frontotemporal dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
LEP P41159 leptin 0.46 0.349 0.846
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
LMNA P02545 lamin A/C 1.00 0.384 0.885
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
CLU P10909 clusterin 7.8E-05 0.426 0.885
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
DKK1 O94907 dickkopf WNT signaling pathway inhibitor 1 0.17 0.439 0.885
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923