Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
CAT | P04040 | catalase | Enzyme | 1.6E-10 | 0.359 | 0.962 |
CCL2 | P13500 | C-C motif chemokine ligand 2 | Signaling | 0.61 | 0.321 | 0.962 |
CHI3L1 | P36222 | chitinase 3 like 1 | 1.1E-05 | 0.419 | 0.885 | |
CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 |
CST3 | P01034 | cystatin C | 3.9E-03 | 0.436 | 0.808 | |
CTSD | P07339 | cathepsin D | Enzyme | 9.2E-04 | 0.478 | 0.846 |
DISC1 | Q9NRI5 | DISC1 scaffold protein | 1.7E-06 | 0.548 | 0.769 | |
DNMT3A | Q9Y6K1 | DNA methyltransferase 3 alpha | 7.4E-39 | 0.445 | 0.846 | |
GFAP | P14136 | glial fibrillary acidic protein | 1.5E-06 | 0.421 | 0.885 | |
GLS | O94925 | glutaminase | Enzyme | 0.96 | 0.489 | 0.808 |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
HFE | Q30201 | homeostatic iron regulator | 2.6E-08 | 0.436 | 0.846 | |
IL18 | Q14116 | interleukin 18 | 3.1E-02 | 0.365 | 0.923 | |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
LAMC2 | Q13753 | laminin subunit gamma 2 | Enzyme modulator | 2.9E-12 | 0.389 | 0.923 |
LBP | P18428 | lipopolysaccharide binding protein | 4.2E-15 | 0.525 | 0.808 | |
LEP | P41159 | leptin | 0.46 | 0.349 | 0.846 | |
LRRK2 | Q5S007 | leucine rich repeat kinase 2 | Kinase | 2.6E-30 | 0.510 | 0.808 |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
NOS3 | P29474 | nitric oxide synthase 3 | 6.7E-07 | 0.378 | 0.885 | |
NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | Transporter | 6.5E-06 | 0.518 | 0.692 |