Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
SMAD3 | P84022 | SMAD family member 3 | Transcription factor | 0.80 | 0.415 | 0.923 |
PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 | |
FKRP | Q9H9S5 | fukutin related protein | 9.8E-06 | 0.513 | 0.731 | |
STAR | P49675 | steroidogenic acute regulatory protein | 8.8E-11 | 0.513 | 0.808 | |
TK2 | O00142 | thymidine kinase 2 | Kinase | 3.9E-07 | 0.585 | 0.615 |
TXNRD2 | Q9NNW7 | thioredoxin reductase 2 | Enzyme | 3.5E-11 | 0.548 | 0.731 |
MC2R | Q01718 | melanocortin 2 receptor | G-protein coupled receptor | 3.1E-04 | 0.582 | 0.654 |
NNT | Q13423 | nicotinamide nucleotide transhydrogenase | Enzyme | 0.97 | 0.601 | 0.577 |
PALLD | Q8WX93 | palladin, cytoskeletal associated protein | 5.3E-06 | 0.628 | 0.615 | |
MRAP | Q8TCY5 | melanocortin 2 receptor accessory protein | 2.1E-03 | 0.674 | 0.500 | |
STRN4 | Q9NRL3 | striatin 4 | 0.99 | 0.792 | 0.346 |