Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
TLR4 | O00206 | toll like receptor 4 | 4.6E-09 | 0.321 | 0.962 | |
CCL2 | P13500 | C-C motif chemokine ligand 2 | Signaling | 0.61 | 0.321 | 0.962 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
MAPK1 | P28482 | mitogen-activated protein kinase 1 | Kinase | 1.00 | 0.330 | 0.923 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
LEP | P41159 | leptin | 0.46 | 0.349 | 0.846 | |
NLRP3 | Q96P20 | NLR family pyrin domain containing 3 | 8.1E-04 | 0.361 | 0.962 | |
SERPINE1 | P05121 | serpin family E member 1 | Enzyme modulator | 4.4E-02 | 0.359 | 0.885 |
AGT | P01019 | angiotensinogen | Enzyme modulator | 5.0E-08 | 0.367 | 0.923 |
TLR2 | O60603 | toll like receptor 2 | 1.0E-06 | 0.361 | 0.923 | |
CXCR4 | P61073 | C-X-C motif chemokine receptor 4 | G-protein coupled receptor | 1.8E-02 | 0.362 | 0.923 |
MIR21 | microRNA 21 | 0.363 | 0.846 | |||
FN1 | P02751 | fibronectin 1 | Signaling | 1.4E-03 | 0.365 | 0.962 |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
ADIPOQ | Q15848 | adiponectin, C1Q and collagen domain containing | 4.6E-09 | 0.376 | 0.885 | |
EZH2 | Q15910 | enhancer of zeste 2 polycomb repressive complex 2 subunit | Epigenetic regulator | 1.00 | 0.376 | 0.885 |