Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
JUP P14923 junction plakoglobin 8.0E-04 0.628 0.500
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
SON P18583 SON DNA binding protein 1.00 0.565 0.769
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
RIPK4 P57078 receptor interacting serine/threonine kinase 4 Kinase 4.0E-03 0.565 0.654
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
TCHH Q07283 trichohyalin 4.7E-24 0.736 0.269
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808
SOS2 Q07890 SOS Ras/Rho guanine nucleotide exchange factor 2 Enzyme modulator 1.00 0.608 0.692
CDK13 Q14004 cyclin dependent kinase 13 Kinase 0.91 0.606 0.692
TTC37 Q6PGP7 tetratricopeptide repeat domain 37 1.7E-29 0.626 0.654
KRT25 Q7Z3Z0 keratin 25 4.6E-09 0.736 0.269
RIT1 Q92963 Ras like without CAAX 1 Enzyme modulator 0.13 0.527 0.808
USP9X Q93008 ubiquitin specific peptidase 9 X-linked 1.00 0.502 0.846
CCDC47 Q96A33 coiled-coil domain containing 47 6.1E-08 0.678 0.462
GAN Q9H2C0 gigaxonin 2.5E-02 0.674 0.500
CERT1 Q9Y5P4 ceramide transporter 1 Transporter 0.67 0.674 0.500
ST14 Q9Y5Y6 suppression of tumorigenicity 14 Enzyme 0.56 0.514 0.769