Disease: CNS disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SST P61278 somatostatin Signaling 0.34 0.399 0.885
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
IL33 O95760 interleukin 33 8.3E-10 0.409 0.885
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
ACKR3 P25106 atypical chemokine receptor 3 G-protein coupled receptor 0.39 0.428 0.885
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CXCR6 O00574 C-X-C motif chemokine receptor 6 G-protein coupled receptor 5.7E-05 0.448 0.885
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808