Disease: Achondroplasia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
COL10A1 Q03692 collagen type X alpha 1 chain Extracellular structure 3.0E-05 0.619 0.500
SLC20A1 Q8WUM9 solute carrier family 20 member 1 Transporter 6.7E-02 0.582 0.577
NPR2 P20594 natriuretic peptide receptor 2 Kinase 4.2E-05 0.573 0.615
POU1F1 P28069 POU class 1 homeobox 1 4.5E-02 0.548 0.654
MSX1 P28360 msh homeobox 1 Transcription factor 0.17 0.525 0.731
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
DCN P07585 decorin 0.31 0.457 0.808
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
SNAI1 O95863 snail family transcriptional repressor 1 0.22 0.474 0.808
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
CYP2C19 P33261 cytochrome P450 family 2 subfamily C member 19 6.5E-20 0.467 0.846
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
FGF1 P05230 fibroblast growth factor 1 Signaling 0.44 0.507 0.846
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
PTHLH P12272 parathyroid hormone like hormone 0.81 0.453 0.846
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885