Disease: Acidosis, Lactic
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
USP18 Q9UMW8 ubiquitin specific peptidase 18 1.5E-03 0.601 0.615
UQCRFS1 P47985 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 0.19 0.558 0.654
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TTR P02766 transthyretin Transporter 0.52 0.423 0.885
TIMMDC1 Q9NPL8 translocase of inner mitochondrial membrane domain containing 1 1.1E-08 0.653 0.538
TFAM Q00059 transcription factor A, mitochondrial 0.17 0.529 0.731
TYMP P19971 thymidine phosphorylase Enzyme 1.2E-04 0.495 0.769
TXNIP Q9H3M7 thioredoxin interacting protein 0.16 0.490 0.731
SCO2 O43819 synthesis of cytochrome C oxidase 2 Enzyme 7.5E-07 0.479 0.846
SLC5A2 P31639 solute carrier family 5 member 2 Transporter 4.9E-14 0.499 0.769
SLC25A3 Q00325 solute carrier family 25 member 3 Transporter 7.5E-02 0.566 0.692
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846
RRM2B Q7LG56 ribonucleotide reductase regulatory TP53 inducible subunit M2B Enzyme 2.4E-03 0.527 0.769
PTGS1 P23219 prostaglandin-endoperoxide synthase 1 Enzyme 6.2E-07 0.460 0.885
PTBP1 P26599 polypyrimidine tract binding protein 1 1.00 0.517 0.769
NDUFS8 O00217 NADH:ubiquinone oxidoreductase core subunit S8 Enzyme 0.17 0.636 0.538
NDUFS2 O75306 NADH:ubiquinone oxidoreductase core subunit S2 Enzyme 1.4E-03 0.601 0.654
NDUFS1 P28331 NADH:ubiquinone oxidoreductase core subunit S1 Enzyme 6.6E-11 0.595 0.692
MB P02144 myoglobin 3.1E-02 0.556 0.731
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
MTO1 Q9Y2Z2 mitochondrial tRNA translation optimization 1 7.4E-06 0.670 0.462
MIPEP Q99797 mitochondrial intermediate peptidase Enzyme 1.6E-15 0.666 0.615
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
KARS1 Q15046 lysyl-tRNA synthetase 1 Enzyme 4.2E-09 0.636 0.577