Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
ERCC6 | P0DP91 Q03468 | ERCC excision repair 6, chromatin remodeling factor | 5.2E-22 | 0.507 | 0.808 | |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
SLC22A18 | Q96BI1 | solute carrier family 22 member 18 | Transporter | 6.5E-06 | 0.595 | 0.692 |
ROCK1 | Q13464 | Rho associated coiled-coil containing protein kinase 1 | Kinase | 1.00 | 0.513 | 0.731 |
PPP2R1B | P30154 | protein phosphatase 2 scaffold subunit Abeta | Enzyme | 3.0E-15 | 0.678 | 0.423 |