Source: CLINVAR ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERCC6 P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 5.2E-22 0.507 0.808
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
SLC22A18 Q96BI1 solute carrier family 22 member 18 Transporter 6.5E-06 0.595 0.692
ROCK1 Q13464 Rho associated coiled-coil containing protein kinase 1 Kinase 1.00 0.513 0.731
PPP2R1B P30154 protein phosphatase 2 scaffold subunit Abeta Enzyme 3.0E-15 0.678 0.423