Disease: Acanthosis Nigricans
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KRT18 P05783 keratin 18 0.73 0.530 0.692
AKT2 P31751 AKT serine/threonine kinase 2 Kinase 0.64 0.474 0.769
XRCC4 Q13426 X-ray repair cross complementing 4 8.3E-07 0.528 0.769
CUL4B Q13620 cullin 4B Enzyme 1.00 0.556 0.769
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
CLDN1 O95832 claudin 1 Cell-cell junction 1.0E-03 0.481 0.808
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
LEP P41159 leptin 0.46 0.349 0.846
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
SERPINF1 P36955 serpin family F member 1 Enzyme modulator 7.8E-08 0.460 0.846
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
PNPLA2 Q96AD5 patatin like phospholipase domain containing 2 Enzyme 4.1E-03 0.511 0.846
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
LMNA P02545 lamin A/C 1.00 0.384 0.885
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
TGFA P01135 transforming growth factor alpha Signaling 0.72 0.432 0.885