Disease: Diabetic Neuropathies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
BAD Q92934 BCL2 associated agonist of cell death 4.6E-03 0.553 0.769
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
NGFR P08138 nerve growth factor receptor Receptor 9.8E-02 0.477 0.846
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962