Disease: Mixed anxiety and depressive disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
DNASE1L3 Q13609 deoxyribonuclease 1 like 3 3.0E-05 0.575 0.769
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
GRM2 Q14416 glutamate metabotropic receptor 2 G-protein coupled receptor 0.12 0.582 0.577
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692
KRT7 P08729 keratin 7 3.1E-12 0.463 0.808
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
OXTR P30559 oxytocin receptor G-protein coupled receptor 7.1E-04 0.541 0.769
SCLY Q96I15 selenocysteine lyase Enzyme 2.3E-09 0.530 0.731
SLC45A2 Q9UMX9 solute carrier family 45 member 2 Transporter 1.7E-06 0.626 0.538
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
TAL1 P17542 TAL bHLH transcription factor 1, erythroid differentiation factor Transcription factor 0.57 0.505 0.731