Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
EPHA1 P21709 EPH receptor A1 Kinase 1.5E-23 0.544 0.731
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 4.2E-04 0.532 0.654
CHRNB2 P17787 cholinergic receptor nicotinic beta 2 subunit Ion channel 7.3E-04 0.617 0.308
HLA-DRB5 Q30154 major histocompatibility complex, class II, DR beta 5 Immune response 3.6E-07 0.608 0.731
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
A2M P01023 alpha-2-macroglobulin Enzyme modulator 4.5E-11 0.529 0.769
ABI3 Q9P2A4 ABI family member 3 Enzyme modulator 5.0E-05 0.716 0.231
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808
ENO1 P06733 enolase 1 Enzyme 1.9E-05 0.481 0.885
DHCR24 Q15392 24-dehydrocholesterol reductase Enzyme 3.1E-02 0.498 0.769
TPI1 P60174 triosephosphate isomerase 1 Enzyme 3.0E-02 0.517 0.846
TF P02787 transferrin Enzyme 4.1E-08 0.527 0.846
TPP1 O14773 tripeptidyl peptidase 1 Enzyme 6.3E-07 0.551 0.808
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
ADAMTS1 Q9UHI8 ADAM metallopeptidase with thrombospondin type 1 motif 1 Enzyme 0.72 0.555 0.654
DPYSL2 Q16555 dihydropyrimidinase like 2 Enzyme 0.99 0.585 0.692