Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
EPHA1 | P21709 | EPH receptor A1 | Kinase | 1.5E-23 | 0.544 | 0.731 |
CHRNA7 | P36544 Q494W8 | cholinergic receptor nicotinic alpha 7 subunit | Ion channel | 4.2E-04 | 0.532 | 0.654 |
CHRNB2 | P17787 | cholinergic receptor nicotinic beta 2 subunit | Ion channel | 7.3E-04 | 0.617 | 0.308 |
HLA-DRB5 | Q30154 | major histocompatibility complex, class II, DR beta 5 | Immune response | 3.6E-07 | 0.608 | 0.731 |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
A2M | P01023 | alpha-2-macroglobulin | Enzyme modulator | 4.5E-11 | 0.529 | 0.769 |
ABI3 | Q9P2A4 | ABI family member 3 | Enzyme modulator | 5.0E-05 | 0.716 | 0.231 |
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
SOD2 | P04179 | superoxide dismutase 2 | Enzyme | 0.15 | 0.379 | 0.923 |
MPO | P05164 | myeloperoxidase | Enzyme | 7.1E-15 | 0.377 | 0.923 |
F2 | P00734 | coagulation factor II, thrombin | Enzyme | 1.1E-03 | 0.415 | 0.885 |
PLAU | P00749 | plasminogen activator, urokinase | Enzyme | 2.3E-06 | 0.425 | 0.923 |
ACHE | P22303 | acetylcholinesterase (Cartwright blood group) | Enzyme | 1.00 | 0.445 | 0.885 |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
WWOX | Q9NZC7 | WW domain containing oxidoreductase | Enzyme | 1.2E-15 | 0.453 | 0.808 |
ENO1 | P06733 | enolase 1 | Enzyme | 1.9E-05 | 0.481 | 0.885 |
DHCR24 | Q15392 | 24-dehydrocholesterol reductase | Enzyme | 3.1E-02 | 0.498 | 0.769 |
TPI1 | P60174 | triosephosphate isomerase 1 | Enzyme | 3.0E-02 | 0.517 | 0.846 |
TF | P02787 | transferrin | Enzyme | 4.1E-08 | 0.527 | 0.846 |
TPP1 | O14773 | tripeptidyl peptidase 1 | Enzyme | 6.3E-07 | 0.551 | 0.808 |
PSEN2 | P49810 | presenilin 2 | Enzyme | 5.4E-04 | 0.550 | 0.654 |
BACE1 | P56817 | beta-secretase 1 | Enzyme | 0.88 | 0.559 | 0.769 |
ADAMTS1 | Q9UHI8 | ADAM metallopeptidase with thrombospondin type 1 motif 1 | Enzyme | 0.72 | 0.555 | 0.654 |
DPYSL2 | Q16555 | dihydropyrimidinase like 2 | Enzyme | 0.99 | 0.585 | 0.692 |