Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CD2AP Q9Y5K6 CD2 associated protein 0.23 0.558 0.731
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 4.2E-04 0.532 0.654
CLU P10909 clusterin 7.8E-05 0.426 0.885
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MIR146A microRNA 146a 0.398 0.885
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962