Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
ACHE | P22303 | acetylcholinesterase (Cartwright blood group) | Enzyme | 1.00 | 0.445 | 0.885 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
BCHE | P06276 | butyrylcholinesterase | 1.1E-13 | 0.447 | 0.923 | |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
CD2AP | Q9Y5K6 | CD2 associated protein | 0.23 | 0.558 | 0.731 | |
CHRNA7 | P36544 Q494W8 | cholinergic receptor nicotinic alpha 7 subunit | Ion channel | 4.2E-04 | 0.532 | 0.654 |
CLU | P10909 | clusterin | 7.8E-05 | 0.426 | 0.885 | |
CST3 | P01034 | cystatin C | 3.9E-03 | 0.436 | 0.808 | |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
GSK3B | P49841 | glycogen synthase kinase 3 beta | Kinase | 0.96 | 0.430 | 0.846 |
HFE | Q30201 | homeostatic iron regulator | 2.6E-08 | 0.436 | 0.846 | |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
MIR146A | microRNA 146a | 0.398 | 0.885 | |||
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
NOS3 | P29474 | nitric oxide synthase 3 | 6.7E-07 | 0.378 | 0.885 | |
PPARG | P37231 | peroxisome proliferator activated receptor gamma | Nuclear receptor | 2.9E-02 | 0.358 | 0.885 |
PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |