Disease: Plaque, Amyloid
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846
HTT P42858 huntingtin 1.00 0.548 0.654
MAOB P27338 monoamine oxidase B 1.00 0.533 0.808
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
CYP46A1 Q9Y6A2 cytochrome P450 family 46 subfamily A member 1 Enzyme 0.99 0.659 0.500
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
TTR P02766 transthyretin Transporter 0.52 0.423 0.885
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
CR1 P17927 complement C3b/C4b receptor 1 (Knops blood group) 1.6E-35 0.533 0.808
ABCA7 Q8IZY2 ATP binding cassette subfamily A member 7 Transporter 2.1E-55 0.644 0.577
TAS2R62P taste 2 receptor member 62 pseudogene 0.729 0.192