| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| ACHE | P22303 | acetylcholinesterase (Cartwright blood group) | Enzyme | 1.00 | 0.445 | 0.885 |
| APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
| APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
| BACE1 | P56817 | beta-secretase 1 | Enzyme | 0.88 | 0.559 | 0.769 |
| BCHE | P06276 | butyrylcholinesterase | 1.1E-13 | 0.447 | 0.923 | |
| BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
| CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
| CDK5 | Q00535 | cyclin dependent kinase 5 | Kinase | 0.14 | 0.495 | 0.846 |
| CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 |
| CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
| GRAP2 | O75791 | GRB2 related adaptor protein 2 | 1.5E-04 | 0.394 | 0.923 | |
| GSK3B | P49841 | glycogen synthase kinase 3 beta | Kinase | 0.96 | 0.430 | 0.846 |
| IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
| IGF1R | P08069 | insulin like growth factor 1 receptor | Kinase | 0.97 | 0.399 | 0.885 |
| IL1A | P01583 | interleukin 1 alpha | 1.6E-04 | 0.333 | 0.962 | |
| LAMC2 | Q13753 | laminin subunit gamma 2 | Enzyme modulator | 2.9E-12 | 0.389 | 0.923 |
| LEP | P41159 | leptin | 0.46 | 0.349 | 0.846 | |
| MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
| MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
| PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
| PSEN2 | P49810 | presenilin 2 | Enzyme | 5.4E-04 | 0.550 | 0.654 |
| TAS2R64P | taste 2 receptor member 64 pseudogene | 0.678 | 0.385 | |||
| TFF1 | P04155 | trefoil factor 1 | Signaling | 8.9E-04 | 0.529 | 0.769 |
| TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
| TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 |