Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ABCA2 | Q9BZC7 | ATP binding cassette subfamily A member 2 | Transporter | 1.00 | 0.670 | 0.615 |
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
ACHE | P22303 | acetylcholinesterase (Cartwright blood group) | Enzyme | 1.00 | 0.445 | 0.885 |
ADAM10 | O14672 | ADAM metallopeptidase domain 10 | 1.00 | 0.489 | 0.846 | |
ANXA1 | P04083 | annexin A1 | 1.2E-07 | 0.442 | 0.885 | |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
BCHE | P06276 | butyrylcholinesterase | 1.1E-13 | 0.447 | 0.923 | |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
CDCA5 | Q96FF9 | cell division cycle associated 5 | 1.2E-03 | 0.563 | 0.808 | |
CDK5 | Q00535 | cyclin dependent kinase 5 | Kinase | 0.14 | 0.495 | 0.846 |
CDK5R1 | Q15078 | cyclin dependent kinase 5 regulatory subunit 1 | Enzyme modulator | 0.91 | 0.529 | 0.808 |
CLU | P10909 | clusterin | 7.8E-05 | 0.426 | 0.885 | |
CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 |
CST3 | P01034 | cystatin C | 3.9E-03 | 0.436 | 0.808 | |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
CYP2D6 | P10635 | cytochrome P450 family 2 subfamily D member 6 | 1.1E-25 | 0.437 | 0.885 | |
DAPK1 | P53355 | death associated protein kinase 1 | Kinase | 1.00 | 0.472 | 0.808 |
DPYSL2 | Q16555 | dihydropyrimidinase like 2 | Enzyme | 0.99 | 0.585 | 0.692 |
EHMT1 | Q9H9B1 | euchromatic histone lysine methyltransferase 1 | Epigenetic regulator | 1.00 | 0.460 | 0.808 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
FANCD2 | Q9BXW9 | FA complementation group D2 | 1.1E-30 | 0.479 | 0.885 |