Disease: Pick Disease of the Brain
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MFSD8 Q8NHS3 major facilitator superfamily domain containing 8 2.5E-12 0.682 0.231
STH Q8IWL8 saitohin 0.705 0.385
UBQLN2 Q9UHD9 ubiquilin 2 0.85 0.656 0.462
TMEM106B Q9NUM4 transmembrane protein 106B 0.33 0.590 0.462
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
TAF15 Q92804 TATA-box binding protein associated factor 15 Nucleic acid binding 0.17 0.626 0.500
INA Q16352 internexin neuronal intermediate filament protein alpha 1.5E-08 0.633 0.500
MATR3 P43243 matrin 3 1.00 0.631 0.538
SCRN1 Q12765 secernin 1 2.5E-03 0.695 0.538
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538
PCBP2 Q15366 poly(rC) binding protein 2 Enzyme 1.00 0.647 0.577
TIA1 P31483 TIA1 cytotoxic granule associated RNA binding protein 0.27 0.595 0.577
SORT1 Q99523 sortilin 1 Transporter 1.00 0.573 0.615
PNO1 Q9NRX1 partner of NOB1 homolog 0.23 0.564 0.615
MAK16 Q9BXY0 MAK16 homolog 0.96 0.566 0.615
HTT P42858 huntingtin 1.00 0.548 0.654
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
SFPQ P23246 splicing factor proline and glutamine rich Nucleic acid binding 1.00 0.593 0.654
HNRNPA1P10 heterogeneous nuclear ribonucleoprotein A1 pseudogene 10 0.631 0.654
EWSR1 Q01844 EWS RNA binding protein 1 Nucleic acid binding 1.00 0.474 0.692
SRRM2 Q9UQ35 serine/arginine repetitive matrix 2 1.00 0.564 0.692
RBMS3 Q6XE24 RNA binding motif single stranded interacting protein 3 0.21 0.553 0.692
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
NEFL P07196 neurofilament light 0.488 0.769
PFN1 P07737 profilin 1 0.73 0.565 0.769