Disease: Inflammatory pain
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808
BDKRB1 P46663 bradykinin receptor B1 G-protein coupled receptor 4.7E-03 0.619 0.731
CALCA P01258 P06881 calcitonin related polypeptide alpha Signaling 1.6E-02 0.416 0.923
CCKBR P32239 cholecystokinin B receptor G-protein coupled receptor 2.1E-06 0.573 0.615
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
CNR2 P34972 cannabinoid receptor 2 G-protein coupled receptor 6.5E-06 0.509 0.846
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
GRIN1 Q05586 glutamate ionotropic receptor NMDA type subunit 1 Ion channel 0.98 0.561 0.692
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
KNG1 P01042 kininogen 1 Enzyme modulator 3.2E-10 0.481 0.885
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
MC1R Q01726 melanocortin 1 receptor G-protein coupled receptor 8.1E-11 0.524 0.808
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
P2RX2 Q9UBL9 purinergic receptor P2X 2 Ion channel 9.7E-13 0.585 0.769