Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
TLR4 | O00206 | toll like receptor 4 | 4.6E-09 | 0.321 | 0.962 | |
IL1RN | P18510 | interleukin 1 receptor antagonist | 3.1E-02 | 0.373 | 0.923 | |
SLC2A1 | P11166 | solute carrier family 2 member 1 | Transporter | 0.99 | 0.388 | 0.808 |
HMOX1 | P09601 | heme oxygenase 1 | 9.7E-03 | 0.381 | 0.923 | |
MECP2 | P51608 | methyl-CpG binding protein 2 | Epigenetic regulator | 0.89 | 0.414 | 0.846 |
MAPK3 | P27361 | mitogen-activated protein kinase 3 | Kinase | 3.7E-02 | 0.379 | 0.885 |
TWIST1 | Q15672 | twist family bHLH transcription factor 1 | Transcription factor | 0.34 | 0.397 | 0.846 |
PTH | P01270 | parathyroid hormone | 1.2E-02 | 0.397 | 0.846 | |
CASR | P41180 | calcium sensing receptor | G-protein coupled receptor | 4.7E-02 | 0.410 | 0.846 |
HTC2 | hypertrichosis 2 (generalized, congenital) | 0.392 | 0.808 | |||
COL1A1 | P02452 | collagen type I alpha 1 chain | 1.00 | 0.430 | 0.808 | |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
DMD | P11532 | dystrophin | 1.00 | 0.423 | 0.923 | |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
INSR | P06213 | insulin receptor | Kinase | 3.6E-05 | 0.432 | 0.846 |
SLC6A4 | P31645 | solute carrier family 6 member 4 | Transporter | 0.25 | 0.429 | 0.808 |
ACHE | P22303 | acetylcholinesterase (Cartwright blood group) | Enzyme | 1.00 | 0.445 | 0.885 |
TBX1 | O43435 | T-box transcription factor 1 | Transcription factor | 0.84 | 0.433 | 0.808 |
TSC2 | P49815 | TSC complex subunit 2 | Enzyme modulator | 1.00 | 0.439 | 0.808 |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
TSC1 | Q92574 | TSC complex subunit 1 | 1.00 | 0.440 | 0.808 |