Disease: Progressive cerebellar ataxia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AFG3L2 Q9Y4W6 AFG3 like matrix AAA peptidase subunit 2 Enzyme 5.3E-09 0.588 0.462
ANO10 Q9NW15 anoctamin 10 1.0E-14 0.663 0.500
APTX Q7Z2E3 aprataxin Nucleic acid binding 4.0E-10 0.590 0.500
ATN1 P54259 atrophin 1 1.00 0.409 0.885
ATXN10 Q9UBB4 ataxin 10 3.5E-04 0.650 0.385
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
ATXN3 P54252 ataxin 3 Enzyme 0.11 0.521 0.808
ATXN7 O15265 ataxin 7 0.96 0.581 0.654
ATXN8 Q156A1 ataxin 8 0.743 0.269
ATXN8OS P0DMR3 ATXN8 opposite strand lncRNA 0.650 0.423
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769
COQ2 Q96H96 coenzyme Q2, polyprenyltransferase Enzyme 1.3E-03 0.590 0.731
DARS2 Q6PI48 aspartyl-tRNA synthetase 2, mitochondrial Enzyme 9.8E-13 0.638 0.577
DKK1 O94907 dickkopf WNT signaling pathway inhibitor 1 0.17 0.439 0.885
EEF2 P13639 eukaryotic translation elongation factor 2 Enzyme 1.00 0.599 0.731
ELOVL4 Q9GZR5 ELOVL fatty acid elongase 4 Enzyme 0.83 0.601 0.577
ERCC8 Q13216 ERCC excision repair 8, CSA ubiquitin ligase complex subunit 2.8E-15 0.551 0.885
FGF14 Q92915 fibroblast growth factor 14 Signaling 0.91 0.619 0.692
FXN Q16595 frataxin Enzyme 0.34 0.510 0.654
GBA2 Q9HCG7 glucosylceramidase beta 2 2.0E-20 0.636 0.654
GRID2 O43424 glutamate ionotropic receptor delta type subunit 2 Ion channel 1.00 0.670 0.500
HTT P42858 huntingtin 1.00 0.548 0.654
ITPR1 Q14643 inositol 1,4,5-trisphosphate receptor type 1 Ion channel 1.00 0.534 0.846
KCNC3 Q14003 potassium voltage-gated channel subfamily C member 3 Ion channel 0.21 0.705 0.462
KCND3 Q9UK17 potassium voltage-gated channel subfamily D member 3 Ion channel 0.99 0.619 0.615