Disease: Frontotemporal dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
ITGB2 P05107 integrin subunit beta 2 Receptor 5.1E-15 0.444 0.923
KHDRBS1 Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 0.99 0.457 0.846
LAD1 O00515 ladinin 1 Cellular structure 1.8E-14 0.584 0.731
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MCIDAS D6RGH6 multiciliate differentiation and DNA synthesis associated cell cycle protein 1.3E-02 0.566 0.769
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MSMB P08118 microseminoprotein beta Signaling 1.6E-02 0.498 0.846
NEFL P07196 neurofilament light 0.488 0.769
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
NRGN Q92686 neurogranin 0.48 0.608 0.615
NUP62 P37198 nucleoporin 62 Transporter 0.95 0.470 0.885
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
PSPH P78330 phosphoserine phosphatase Enzyme 9.7E-04 0.570 0.808
PSPN O60542 persephin Signaling 1.1E-04 0.608 0.769