Disease: Cognition Disorders
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
AQP4 P55087 aquaporin 4 Ion channel 2.3E-03 0.456 0.885
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846
BMI1 P35226 BMI1 proto-oncogene, polycomb ring finger 0.94 0.448 0.808
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CALB1 P05937 calbindin 1 Calcium-binding protein 0.24 0.606 0.615
CAPN1 P07384 calpain 1 Enzyme 5.9E-10 0.539 0.808
CASP2 P42575 caspase 2 Enzyme 1.5E-03 0.565 0.731
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
CHRFAM7A P36544 Q494W8 CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion 2.3E-04 0.659 0.385
CHRNA4 P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 8.5E-05 0.492 0.808
CLU P10909 clusterin 7.8E-05 0.426 0.885
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885