Disease: Apathy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CSF1R P07333 colony stimulating factor 1 receptor Kinase 0.13 0.448 0.808
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
DNAJC13 O75165 DnaJ heat shock protein family (Hsp40) member C13 1.00 0.682 0.577
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
EIF4G1 Q04637 eukaryotic translation initiation factor 4 gamma 1 Nucleic acid binding 1.00 0.553 0.808
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
HTRA2 O43464 HtrA serine peptidase 2 3.6E-03 0.542 0.692
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MCIDAS D6RGH6 multiciliate differentiation and DNA synthesis associated cell cycle protein 1.3E-02 0.566 0.769
PARK7 Q99497 Parkinsonism associated deglycase Enzyme 0.75 0.535 0.808
PINK1 Q9BXM7 PTEN induced kinase 1 Kinase 1.9E-10 0.516 0.769
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923