| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| A2M | P01023 | alpha-2-macroglobulin | Enzyme modulator | 4.5E-11 | 0.529 | 0.769 |
| ABI3 | Q9P2A4 | ABI family member 3 | Enzyme modulator | 5.0E-05 | 0.716 | 0.231 |
| ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
| ACHE | P22303 | acetylcholinesterase (Cartwright blood group) | Enzyme | 1.00 | 0.445 | 0.885 |
| APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
| APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
| BACE1 | P56817 | beta-secretase 1 | Enzyme | 0.88 | 0.559 | 0.769 |
| BCHE | P06276 | butyrylcholinesterase | 1.1E-13 | 0.447 | 0.923 | |
| BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
| BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
| CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
| CLU | P10909 | clusterin | 7.8E-05 | 0.426 | 0.885 | |
| CST3 | P01034 | cystatin C | 3.9E-03 | 0.436 | 0.808 | |
| CYP2D6 | P10635 | cytochrome P450 family 2 subfamily D member 6 | 1.1E-25 | 0.437 | 0.885 | |
| IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
| IGF1R | P08069 | insulin like growth factor 1 receptor | Kinase | 0.97 | 0.399 | 0.885 |
| IGF2 | P01344 | insulin like growth factor 2 | 4.4E-02 | 0.390 | 0.885 | |
| IGF2R | P11717 | insulin like growth factor 2 receptor | Receptor | 1.00 | 0.518 | 0.731 |
| INS | P01308 | insulin | 0.30 | 0.445 | 0.923 | |
| INSR | P06213 | insulin receptor | Kinase | 3.6E-05 | 0.432 | 0.846 |
| MAOB | P27338 | monoamine oxidase B | 1.00 | 0.533 | 0.808 | |
| MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
| NOS3 | P29474 | nitric oxide synthase 3 | 6.7E-07 | 0.378 | 0.885 | |
| PLCG2 | P16885 | phospholipase C gamma 2 | Enzyme | 1.00 | 0.588 | 0.808 |
| PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 |