Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ACHE | P22303 | acetylcholinesterase (Cartwright blood group) | Enzyme | 1.00 | 0.445 | 0.885 |
AIF1 | P55008 | allograft inflammatory factor 1 | Calcium-binding protein | 1.9E-06 | 0.521 | 0.808 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
BACE1 | P56817 | beta-secretase 1 | Enzyme | 0.88 | 0.559 | 0.769 |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
BPIFA2 | Q96DR5 | BPI fold containing family A member 2 | 8.0E-07 | 0.608 | 0.808 | |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
CASP2 | P42575 | caspase 2 | Enzyme | 1.5E-03 | 0.565 | 0.731 |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
CHI3L1 | P36222 | chitinase 3 like 1 | 1.1E-05 | 0.419 | 0.885 | |
COX2 | P00403 | cytochrome c oxidase subunit II | Enzyme | 0.352 | 0.962 | |
CSF1R | P07333 | colony stimulating factor 1 receptor | Kinase | 0.13 | 0.448 | 0.808 |
CST3 | P01034 | cystatin C | 3.9E-03 | 0.436 | 0.808 | |
CTSD | P07339 | cathepsin D | Enzyme | 9.2E-04 | 0.478 | 0.846 |
DCTN4 | Q9UJW0 | dynactin subunit 4 | 0.73 | 0.472 | 0.846 | |
DLG4 | P78352 | discs large MAGUK scaffold protein 4 | Receptor | 1.00 | 0.595 | 0.654 |
DYRK1A | Q13627 | dual specificity tyrosine phosphorylation regulated kinase 1A | Kinase | 1.00 | 0.533 | 0.769 |
FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
FYN | P06241 | FYN proto-oncogene, Src family tyrosine kinase | Kinase | 0.99 | 0.556 | 0.731 |
GFAP | P14136 | glial fibrillary acidic protein | 1.5E-06 | 0.421 | 0.885 | |
GRK2 | P25098 | G protein-coupled receptor kinase 2 | Kinase | 1.00 | 0.532 | 0.654 |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
GTF2H1 | P32780 | general transcription factor IIH subunit 1 | Transcription factor | 0.99 | 0.469 | 0.846 |
HSP90AA1 | P07900 | heat shock protein 90 alpha family class A member 1 | Chaperone | 0.86 | 0.411 | 0.923 |