Disease: Thrombophilia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CBS P0DN79 P35520 cystathionine beta-synthase Enzyme 3.1E-05 0.465 0.885
CBSL P0DN79 P35520 cystathionine beta-synthase like 0.540 0.808
COPD Pulmonary disease, chronic obstructive, severe early-onset 0.456 0.885
CPB2 Q96IY4 carboxypeptidase B2 Enzyme 2.7E-17 0.536 0.846
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
F10 P00742 coagulation factor X Enzyme 2.3E-06 0.493 0.769
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
MOK Q9UQ07 MOK protein kinase Kinase 8.8E-22 0.476 0.769
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
PADI4 Q9UM07 peptidyl arginine deiminase 4 4.6E-16 0.494 0.808
PROC P04070 protein C, inactivator of coagulation factors Va and VIIIa Enzyme 1.9E-05 0.504 0.808
SELP P16109 selectin P 5.0E-32 0.460 0.769
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
VKORC1 Q9BQB6 vitamin K epoxide reductase complex subunit 1 Enzyme 0.16 0.603 0.731