Disease: Ichthyoses
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA12 Q86UK0 ATP binding cassette subfamily A member 12 Transporter 2.9E-15 0.610 0.654
ALDH3A2 P51648 aldehyde dehydrogenase 3 family member A2 9.4E-06 0.619 0.769
ALOX12B O75342 arachidonate 12-lipoxygenase, 12R type Enzyme 7.6E-04 0.603 0.577
ALOXE3 Q9BYJ1 arachidonate lipoxygenase 3 Enzyme 5.1E-20 0.644 0.538
AP1S1 P61966 adaptor related protein complex 1 subunit sigma 1 Transporter 1.0E-01 0.743 0.308
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CARD14 Q9BXL6 caspase recruitment domain family member 14 1.2E-19 0.546 0.846
COL7A1 Q02388 collagen type VII alpha 1 chain Receptor 2.4E-40 0.545 0.808
CYP4F22 Q6NT55 cytochrome P450 family 4 subfamily F member 22 Enzyme 5.3E-06 0.705 0.462
DNAJC21 Q5F1R6 DnaJ heat shock protein family (Hsp40) member C21 2.1E-07 0.606 0.731
DSP P15924 desmoplakin Cellular structure 1.00 0.514 0.808
ELOVL4 Q9GZR5 ELOVL fatty acid elongase 4 Enzyme 0.83 0.601 0.577
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
ERCC3 P19447 ERCC excision repair 3, TFIIH core complex helicase subunit Enzyme 3.4E-11 0.504 0.846
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
IL17F Q96PD4 interleukin 17F 3.9E-02 0.480 0.808
IL23A Q9NPF7 interleukin 23 subunit alpha Signaling 0.36 0.415 0.846
KRT1 P04264 keratin 1 0.74 0.575 0.654
KRT10 P13645 keratin 10 2.5E-03 0.579 0.692
KRT14 P02533 keratin 14 2.0E-04 0.530 0.731
KRT16 P08779 keratin 16 1.5E-14 0.565 0.769
KRT6A P02538 keratin 6A 7.0E-05 0.610 0.692
LIPN Q5VXI9 lipase family member N 3.1E-05 0.736 0.423