Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
AIRE | O43918 | autoimmune regulator | 4.0E-12 | 0.516 | 0.808 | |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
CALCA | P01258 P06881 | calcitonin related polypeptide alpha | Signaling | 1.6E-02 | 0.416 | 0.923 |
CCL2 | P13500 | C-C motif chemokine ligand 2 | Signaling | 0.61 | 0.321 | 0.962 |
CCR5 | P51681 | C-C motif chemokine receptor 5 (gene/pseudogene) | G-protein coupled receptor | 4.3E-10 | 0.398 | 0.885 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
CTLA4 | P16410 | cytotoxic T-lymphocyte associated protein 4 | 0.94 | 0.369 | 0.923 | |
CXCL10 | P02778 | C-X-C motif chemokine ligand 10 | Signaling | 0.37 | 0.378 | 0.885 |
CXCL9 | Q07325 | C-X-C motif chemokine ligand 9 | Signaling | 2.9E-03 | 0.462 | 0.808 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
FCRL3 | Q96P31 | Fc receptor like 3 | Cell adhesion | 6.0E-21 | 0.612 | 0.769 |
FOXP3 | Q9BZS1 | forkhead box P3 | 0.99 | 0.368 | 0.846 | |
GAD1 | Q99259 | glutamate decarboxylase 1 | Enzyme | 4.6E-02 | 0.486 | 0.885 |
HLA-A | P04439 | major histocompatibility complex, class I, A | 1.3E-03 | 0.370 | 0.846 | |
HLA-DRB1 | P01911 | major histocompatibility complex, class II, DR beta 1 | Immune response | 1.1E-03 | 0.333 | 0.923 |
HT | Hashimoto thyroiditis | 0.505 | 0.731 | |||
ICAM1 | P05362 | intercellular adhesion molecule 1 | 3.5E-02 | 0.364 | 0.962 | |
IFNA1 | P01562 | interferon alpha 1 | 0.371 | 0.923 | ||
IFNA13 | P01562 | interferon alpha 13 | 0.374 | 0.923 | ||
IFNG | P01579 | interferon gamma | 0.47 | 0.288 | 0.962 | |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
IL17A | Q16552 | interleukin 17A | 4.3E-02 | 0.324 | 0.923 | |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
IL23R | Q5VWK5 | interleukin 23 receptor | Signaling | 5.6E-04 | 0.466 | 0.769 |