Disease: Cholesterol gallstones
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB11 O95342 ATP binding cassette subfamily B member 11 Transporter 1.6E-12 0.566 0.654
ABCB4 P21439 ATP binding cassette subfamily B member 4 Transporter 2.2E-07 0.529 0.615
ABCG5 Q9H222 ATP binding cassette subfamily G member 5 Transporter 3.1E-21 0.592 0.577
ABCG8 Q9H221 ATP binding cassette subfamily G member 8 Transporter 2.4E-20 0.573 0.538
ACAT2 Q9BWD1 acetyl-CoA acetyltransferase 2 Enzyme 5.5E-07 0.686 0.462
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885
ADRB3 P13945 adrenoceptor beta 3 G-protein coupled receptor 2.5E-07 0.533 0.731
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CCK P06307 cholecystokinin 3.3E-05 0.453 0.846
CCKAR P32238 cholecystokinin A receptor G-protein coupled receptor 4.0E-03 0.615 0.500
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
CLDN2 P57739 claudin 2 Cell-cell junction 0.70 0.575 0.692
CLDN3 O15551 claudin 3 Cell-cell junction 0.52 0.558 0.615
CYP7A1 P22680 cytochrome P450 family 7 subfamily A member 1 Enzyme 2.5E-04 0.576 0.615
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
GUSB P08236 glucuronidase beta 4.0E-08 0.530 0.846
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
NPC1L1 Q9UHC9 NPC1 like intracellular cholesterol transporter 1 Transporter 2.3E-20 0.656 0.423
NR1H4 Q96RI1 nuclear receptor subfamily 1 group H member 4 Nuclear receptor 9.4E-04 0.513 0.808
PLA2G2A P14555 phospholipase A2 group IIA Enzyme 9.7E-02 0.488 0.808
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
PPARGC1B Q86YN6 PPARG coactivator 1 beta Transcription factor 0.50 0.569 0.731
RBP4 P02753 retinol binding protein 4 Transporter 0.52 0.493 0.808