Disease: Spinal Muscular Atrophy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
IAPP P10997 islet amyloid polypeptide Signaling 3.2E-03 0.507 0.808
KHDRBS1 Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 0.99 0.457 0.846
LMNA P02545 lamin A/C 1.00 0.384 0.885
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
MIR375 microRNA 375 0.476 0.769
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
NEFL P07196 neurofilament light 0.488 0.769
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885
NUP62 P37198 nucleoporin 62 Transporter 0.95 0.470 0.885
PVALB P20472 parvalbumin Calcium-binding protein 8.7E-02 0.547 0.692
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
SGSM3 Q96HU1 small G protein signaling modulator 3 Enzyme 3.4E-15 0.469 0.808
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SYT1 P21579 synaptotagmin 1 Transporter 0.60 0.412 0.846
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
TIA1 P31483 TIA1 cytotoxic granule associated RNA binding protein 0.27 0.595 0.577