Disease: Plaque, Amyloid
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CAPN2 P17655 calpain 2 Enzyme 3.5E-22 0.590 0.692
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
CYP46A1 Q9Y6A2 cytochrome P450 family 46 subfamily A member 1 Enzyme 0.99 0.659 0.500
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
HSPB2 Q16082 heat shock protein family B (small) member 2 3.3E-04 0.457 0.769
HSPB3 Q12988 heat shock protein family B (small) member 3 6.1E-05 0.448 0.769
HTT P42858 huntingtin 1.00 0.548 0.654
IAPP P10997 islet amyloid polypeptide Signaling 3.2E-03 0.507 0.808
MAP2 P11137 microtubule associated protein 2 1.00 0.537 0.692
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
OGA O60502 O-GlcNAcase 0.97 0.534 0.731
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923