Disease: Postoperative cognitive dysfunction
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885
DCTN4 Q9UJW0 dynactin subunit 4 0.73 0.472 0.846
DLG4 P78352 discs large MAGUK scaffold protein 4 Receptor 1.00 0.595 0.654
FKBP4 Q02790 FKBP prolyl isomerase 4 Enzyme 0.16 0.532 0.769
FKBP5 Q13451 FKBP prolyl isomerase 5 Enzyme 0.73 0.524 0.769
GORASP1 Q9BQQ3 golgi reassembly stacking protein 1 2.0E-02 0.428 0.846
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
KHDRBS1 Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 0.99 0.457 0.846
MIR155 microRNA 155 0.384 0.885
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
NUP62 P37198 nucleoporin 62 Transporter 0.95 0.470 0.885
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
PRKAA1 Q13131 protein kinase AMP-activated catalytic subunit alpha 1 Kinase 0.14 0.453 0.846
PRKAA2 P54646 protein kinase AMP-activated catalytic subunit alpha 2 Kinase 3.5E-08 0.456 0.846
PRKAB1 Q9Y478 protein kinase AMP-activated non-catalytic subunit beta 1 Kinase 5.3E-03 0.460 0.846
PVALB P20472 parvalbumin Calcium-binding protein 8.7E-02 0.547 0.692