Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
H3P10 | H3 histone pseudogene 10 | 0.350 | 0.846 | |||
TERT | O14746 | telomerase reverse transcriptase | Enzyme | 0.99 | 0.374 | 0.846 |
MDM2 | Q00987 | MDM2 proto-oncogene | Nucleic acid binding | 1.00 | 0.362 | 0.846 |
IFNA1 | P01562 | interferon alpha 1 | 0.371 | 0.923 | ||
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
IFNA13 | P01562 | interferon alpha 13 | 0.374 | 0.923 | ||
IGF1R | P08069 | insulin like growth factor 1 receptor | Kinase | 0.97 | 0.399 | 0.885 |
GPT | P24298 | glutamic--pyruvic transaminase | Enzyme | 3.6E-19 | 0.403 | 0.923 |
HTC2 | hypertrichosis 2 (generalized, congenital) | 0.392 | 0.808 | |||
ATN1 | P54259 | atrophin 1 | 1.00 | 0.409 | 0.885 | |
SYT1 | P21579 | synaptotagmin 1 | Transporter | 0.60 | 0.412 | 0.846 |
CDK4 | P11802 | cyclin dependent kinase 4 | Kinase | 6.3E-02 | 0.412 | 0.808 |
ATRX | P46100 | ATRX chromatin remodeler | 1.00 | 0.452 | 0.808 | |
XRCC1 | P18887 | X-ray repair cross complementing 1 | 6.3E-09 | 0.421 | 0.923 | |
IDH1 | O75874 | isocitrate dehydrogenase (NADP(+)) 1 | 2.6E-12 | 0.424 | 0.808 | |
HMGA2 | P52926 | high mobility group AT-hook 2 | Nucleic acid binding | 0.87 | 0.429 | 0.808 |
IDH2 | P48735 | isocitrate dehydrogenase (NADP(+)) 2 | 0.88 | 0.434 | 0.808 | |
YAP1 | P46937 | Yes associated protein 1 | Enzyme modulator | 1.00 | 0.432 | 0.808 |
MKI67 | P46013 | marker of proliferation Ki-67 | 1.3E-28 | 0.431 | 0.808 | |
JUN | P05412 | Jun proto-oncogene, AP-1 transcription factor subunit | Transcription factor | 6.0E-02 | 0.442 | 0.885 |