Disease: Aortic Valve Insufficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923
AKR1C3 P42330 aldo-keto reductase family 1 member C3 Enzyme 7.6E-24 0.529 0.769
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
CAMK2N1 Q7Z7J9 calcium/calmodulin dependent protein kinase II inhibitor 1 0.17 0.716 0.308
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885
CDK2 P24941 cyclin dependent kinase 2 Kinase 0.61 0.456 0.692
CDK5 Q00535 cyclin dependent kinase 5 Kinase 0.14 0.495 0.846
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CXCR6 O00574 C-X-C motif chemokine receptor 6 G-protein coupled receptor 5.7E-05 0.448 0.885
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
DKK1 O94907 dickkopf WNT signaling pathway inhibitor 1 0.17 0.439 0.885
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERG P11308 ETS transcription factor ERG Transcription factor 0.96 0.453 0.808
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923