Disease: Cancer cachexia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AHSA1 O95433 activator of HSP90 ATPase activity 1 1.00 0.396 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
FADD Q13158 Fas associated via death domain 0.53 0.537 0.846
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
LIF P15018 LIF interleukin 6 family cytokine Signaling 0.52 0.483 0.769
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
TRAF6 Q9Y4K3 TNF receptor associated factor 6 Signaling 1.00 0.472 0.808