Disease: secondary acute myeloid leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
SOAT1 P35610 sterol O-acyltransferase 1 Enzyme 7.4E-10 0.424 0.846
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808