Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
NOS2 | P35228 | nitric oxide synthase 2 | 4.0E-15 | 0.364 | 0.923 | |
KIT | P10721 | KIT proto-oncogene, receptor tyrosine kinase | Kinase | 0.98 | 0.366 | 0.808 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
VIM | P08670 | vimentin | 0.71 | 0.372 | 0.846 | |
KDR | P35968 | kinase insert domain receptor | Kinase | 1.00 | 0.378 | 0.885 |
MET | P08581 | MET proto-oncogene, receptor tyrosine kinase | Kinase | 0.97 | 0.380 | 0.846 |
NOS1 | P29475 | nitric oxide synthase 1 | 1.00 | 0.408 | 0.885 | |
PDGFRA | P16234 | platelet derived growth factor receptor alpha | Kinase | 1.00 | 0.415 | 0.808 |
CD68 | P34810 | CD68 molecule | Transporter | 1.4E-06 | 0.408 | 0.808 |
TSC2 | P49815 | TSC complex subunit 2 | Enzyme modulator | 1.00 | 0.439 | 0.808 |
TSC1 | Q92574 | TSC complex subunit 1 | 1.00 | 0.440 | 0.808 | |
DES | P17661 | desmin | 8.8E-03 | 0.460 | 0.846 | |
NF2 | P35240 | neurofibromin 2 | 1.00 | 0.468 | 0.885 | |
PAX8 | Q06710 | paired box 8 | 1.00 | 0.477 | 0.731 | |
MITF | O75030 | melanocyte inducing transcription factor | 0.98 | 0.499 | 0.808 | |
IGFBP7 | Q16270 | insulin like growth factor binding protein 7 | 1.3E-03 | 0.476 | 0.769 | |
CTSK | P43235 | cathepsin K | Enzyme | 3.1E-05 | 0.497 | 0.808 |
ANO1 | Q5XXA6 | anoctamin 1 | Ion channel | 0.87 | 0.516 | 0.769 |
TFEB | P19484 | transcription factor EB | 0.90 | 0.527 | 0.731 | |
NONO | Q15233 | non-POU domain containing octamer binding | Nucleic acid binding | 0.99 | 0.554 | 0.731 |
PMEL | P40967 | premelanosome protein | Signaling | 3.1E-18 | 0.531 | 0.769 |
RAD51B | O15315 | RAD51 paralog B | 2.1E-15 | 0.556 | 0.769 |