Disease: Malignant neoplasm of large intestine
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
CDH1 P12830 cadherin 1 0.15 0.401 0.808
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885
GATA3 P23771 GATA binding protein 3 0.90 0.415 0.846
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
RTEL1 Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 8.9E-10 0.459 0.808
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
SMAD7 O15105 SMAD family member 7 Transcription factor 0.55 0.470 0.769
HNF1B P35680 HNF1 homeobox B Nucleic acid binding 1.00 0.473 0.808
CCND2 P30279 cyclin D2 Enzyme modulator 0.99 0.477 0.808
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731
LRP1 Q07954 LDL receptor related protein 1 1.00 0.482 0.769