Source: BEFREE ×
Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | Enzyme | 1.00 | 0.314 | 0.962 |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
COX2 | P00403 | cytochrome c oxidase subunit II | Enzyme | 0.352 | 0.962 | |
MDM2 | Q00987 | MDM2 proto-oncogene | Nucleic acid binding | 1.00 | 0.362 | 0.846 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
MTCO2P12 | MT-CO2 pseudogene 12 | 0.368 | 0.962 | |||
GSTM1 | P09488 | glutathione S-transferase mu 1 | 2.1E-03 | 0.380 | 0.923 | |
PCNA | P12004 | proliferating cell nuclear antigen | Nucleic acid binding | 0.98 | 0.382 | 0.846 |
GSTP1 | P09211 | glutathione S-transferase pi 1 | 1.4E-02 | 0.383 | 0.923 | |
MMP1 | P03956 | matrix metallopeptidase 1 | Enzyme | 7.7E-18 | 0.385 | 0.885 |
IGF2 | P01344 | insulin like growth factor 2 | 4.4E-02 | 0.390 | 0.885 | |
COMT | P21964 | catechol-O-methyltransferase | Enzyme | 1.1E-06 | 0.400 | 0.923 |
PDCD1 | Q15116 | programmed cell death 1 | 0.42 | 0.402 | 0.846 | |
SLCO6A1 | Q86UG4 | solute carrier organic anion transporter family member 6A1 | Transporter | 2.9E-11 | 0.412 | 0.885 |
GSTK1 | Q9Y2Q3 | glutathione S-transferase kappa 1 | 1.9E-06 | 0.412 | 0.885 | |
CEACAM5 | P06731 | CEA cell adhesion molecule 5 | 4.2E-10 | 0.420 | 0.846 | |
RASSF1 | Q9NS23 | Ras association domain family member 1 | Enzyme modulator | 4.9E-06 | 0.420 | 0.808 |
CYP1A1 | P04798 | cytochrome P450 family 1 subfamily A member 1 | Enzyme | 1.1E-17 | 0.436 | 0.846 |