Disease: Juvenile Myelomonocytic Leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
REG1A P05451 regenerating family member 1 alpha 1.3E-05 0.467 0.846
HOXA9 P31269 homeobox A9 4.4E-05 0.521 0.692
KLF1 Q13351 Kruppel like factor 1 Nucleic acid binding 3.6E-04 0.621 0.462
PCBP4 P57723 poly(rC) binding protein 4 Enzyme 2.4E-03 0.523 0.808
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
PAG1 Q9NWQ8 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 1.8E-02 0.505 0.808
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
PEBP1 P30086 phosphatidylethanolamine binding protein 1 Enzyme modulator 9.2E-02 0.500 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
EIF4E P06730 eukaryotic translation initiation factor 4E Nucleic acid binding 0.94 0.448 0.846
OPN1LW P04000 opsin 1, long wave sensitive G-protein coupled receptor 0.98 0.497 0.808
ELL P55199 elongation factor for RNA polymerase II Cell-cell junction 0.99 0.700 0.308
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885