Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
IDH1 | O75874 | isocitrate dehydrogenase (NADP(+)) 1 | 2.6E-12 | 0.424 | 0.808 | |
FBXW7 | Q969H0 | F-box and WD repeat domain containing 7 | Enzyme modulator | 1.00 | 0.465 | 0.808 |
POLE | Q07864 | DNA polymerase epsilon, catalytic subunit | 8.0E-27 | 0.526 | 0.731 | |
C11orf65 | Q8NCR3 | chromosome 11 open reading frame 65 | 2.0E-14 | 0.670 | 0.462 |