Disease: Colonic Neoplasms
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IFNG P01579 interferon gamma 0.47 0.288 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
LEP P41159 leptin 0.46 0.349 0.846
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885