Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
APOBEC3B Q9UH17 apolipoprotein B mRNA editing enzyme catalytic subunit 3B Enzyme 5.2E-16 0.547 0.731
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CCNE1 P24864 cyclin E1 Enzyme modulator 0.97 0.538 0.731
CDH1 P12830 cadherin 1 0.15 0.401 0.808
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
GPX1 P07203 glutathione peroxidase 1 Enzyme 3.9E-05 0.458 0.923
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
IFNB1 P01574 interferon beta 1 0.421 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGFBP5 P24593 insulin like growth factor binding protein 5 Enzyme modulator 0.96 0.544 0.692
KMT2D O14686 lysine methyltransferase 2D 1.00 0.465 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MDM4 O15151 MDM4 regulator of p53 Nucleic acid binding 1.00 0.461 0.808
MIR145 microRNA 145 0.431 0.846