Disease: Malignant neoplasm of lung
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
BIRC5 O15392 baculoviral IAP repeat containing 5 Enzyme modulator 5.6E-02 0.495 0.731
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CYP1B1 Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 2.2E-05 0.457 0.769
CYP24A1 Q07973 cytochrome P450 family 24 subfamily A member 1 Enzyme 3.2E-23 0.518 0.692
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
DPYD Q12882 dihydropyrimidine dehydrogenase Enzyme 3.4E-22 0.493 0.846
EEF2 P13639 eukaryotic translation elongation factor 2 Enzyme 1.00 0.599 0.731
EFEMP1 Q12805 EGF containing fibulin extracellular matrix protein 1 Extracellular structure 1.00 0.540 0.769
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
FOXM1 Q08050 forkhead box M1 7.4E-04 0.441 0.769