Disease: Alcohol Use Disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ADH1B P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 9.9E-07 0.502 0.846
ADH4 P08319 alcohol dehydrogenase 4 (class II), pi polypeptide Enzyme 8.1E-07 0.641 0.462
ALDH2 P05091 aldehyde dehydrogenase 2 family member Enzyme 3.4E-10 0.457 0.885
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CARTPT Q16568 CART prepropeptide 9.4E-02 0.576 0.692
CHRNA4 P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 8.5E-05 0.492 0.808
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
GABRA2 P47869 gamma-aminobutyric acid type A receptor subunit alpha2 Ion channel 1.00 0.641 0.346
GAL P22466 galanin and GMAP prepropeptide 4.4E-06 0.493 0.846
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885